Vitamin12 is produced only by fungi and bacteria. Human intestinal bacteria also produced appreciable quantities of it. It was effective in a type of anaemia called pernicious anaemia, in as small a quantity as one-millionth part of a gram. Its deficiency in the body occurred usually due to malabsorption from the intestine rather than from malnutrition.
Vitamin B12 is freely soluble in water. It is resistant to boiling in neutral solutions, but is liable to destruction in the presence of alkalies and acids. Other factors that destroy this vitamin are sunlight, alcohol, estrogen (the female hormone), and sleeping pills.
Deficiency of vitamin B12 is caused more frequently by problems of absorption than by dietary inadequacy. The presence of a sufficient quantity of gastric juice is essential to facilitate its absorption in the intestine. calcium and protein-rich food greatly help the absorption of this vitamin from the intestines. The amount of vitamin B12 which is not immediately needed by the body is stored in the liver, which is capable of storing relatively large amounts of this nutrient. Cyanocobalamin is used to treat and prevent the deficiency of Vitamin B12. The deficiency may be caused due to some diseases and treatment the reduce the ability of the body to absorb the vitamin from the food.
About 30 mcg of vitamin B12 are excreted in the normal urine daily. Cyanocobalamin is injected directly into the blood stream. This helps people with severe vitamin B12 deficiency to absorb the vitamin directly. When Cyanocobalamin is injected in a large dose of up to 100 mcg, up to 90 per cent of the quantity is excreted. Since the absorption of vitamin B12 does not take place in the colon, much of the unabsorbed vitamin B12 is excreted in the stools. This vitamin is also secreted in breast milk for the use of babies.
Some side effects of Cyanocobalamin injections are:
- Pain and strain in the calf muscles and feet.
- Heaviness while breathing when you exercise.
- Irregular of fast heart beats.
- Itching, rashes on skin and a slight red coloration on your facial skin.
- Feeling of fatigue all the time.
- Fell very thirsty all the time and tend to urinate frequently.