Cyst on Knuckle: Causes, Home Remedies for Cyst on Finger, Thumb Knuckle

Cyst on knuckles can be due to the inflammation of a hair follicle or a trapped sebum that is released by sebaceous glands. However, knuckles are not the usual areas where sebum gets blocked. There is another possible cause for the cyst on knuckle, the ganglion cyst. The ganglion cyst usually appears on the different areas of the hand, but they mostly develop on the top of a joint or the covering of a tendon and are filled with colorless, thick, and sticky fluid.

Causes of Cyst on Knuckles of Finger and Thumb

The cause of cyst on knuckle or ganglion cyst is not clear to medical science.

Some suggest that it could be the result of trauma or could be a sign of flaw in the tendon sheath, which makes the joint tissue in the knuckle bulge. Cyst knuckle is unpredictable that they can appear all of a sudden but reappear without any apparent reason. Some cyst on knuckle manifests pain and worsens when there is joint motion, while other could have no symptom aside from the unusual appearance of bulge or cyst on knuckle.

Home Remedies and Treatment for Cyst on Knuckle

To determine the cause of your cyst on knuckle, it is advisable for you to consult a dermatologist or a family doctor to properly diagnose the cyst and to determine its treatment.

Meanwhile, it would be better if you avoid hand or finger injuries to prevent having cyst on knuckle. If your cyst on your knuckles is filled with yellowish fluid, the possible cause is trapped sebum in it. Avoid picking the cyst; instead, apply heat compress on the affected knuckle to drain the sebum naturally. Picking on the cyst would lead to the spread of bacteria on your hands and cause other bacterial infection. Wash your hands frequently with anti-bacterial soap for added protection.


  1. Toliver said:

    I have little tiny round clear looking bumps on my knuckles on both the hands. I wonder if they are cysts and can they be removed?

    July 17, 2017
  2. Janie said:

    I accidentally cut my index finger knuckle two months ago and it is still swollen and it is paining. I had got the x-ray done and it is not broken. I am taking antibiotics and have been soaking finger in warm water with Epsom salt. The Ffnger is more swollen when I wake up and swelling goes down during the day.

    August 17, 2017

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