Growth Hormone Deficiency: GHD Symptoms, Treatment and Prevention

Functions of Growth Hormone

  • Growth hormone is a linear polypeptide with 191 amino acids. A significant of the GH in the blood is bound form with GH binding protein.
  • Growth hormone is required for normal growth of the child.
  • GH is produced in the pituitary gland in the brain. Secretion of the GH is controlled by various other hormones produced by the brain.
  • Growth hormone also stimulates the liver to produce insulin like growth factor when it is circulates in the blood.

Deficiency of the Growth Hormone Causes

  • The hypothalamus releases less stimulatory hormone.
  • There is less production of GH by the pituitary gland.
  • There is decrease in the insulin like growth factor.
  • Lack of oxygen supply at birth.
  • Autoimmune condition.

Symptoms of GH Deficiency in Children

  • Short stature.
  • Weight gain is decreased.
  • Teeth development is delayed.
  • Fat around the waist is increased.
  • The child looks young compared to his peers.
  • Puberty is delayed.

In Adults

  • Low in energy
  • Decreased muscle mass.
  • Decrease of strength.
  • Weight gain around the waist.
  • Anxiety, sadness.
  • Dry and thin skin.

Treatment of GH Deficiency

  • Eat regular diet which contains all the necessary healthy food and ingredients such as vitamins, carbohydrates, fats, proteins etc.
  • Regular exercise and sleep is also necessary.
  • Growth hormone therapy with GH injection. This is prescribed by the doctor and the main aim of it is to increase stunted growth and energy.
  • A pituitary tumor which may be the cause of growth hormone deficiency may require surgery or radiation.

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