Protein C and S Deficiency: Treatment for Protein C & S Deficiency

Protein C and S Function

Protein C and S deficiency is a congenital anomaly, it is a disorder which is inherited and passed on from one member of the family to other.

In a normal individual, protein C & S is present in the blood, and prevents formation of clot in the blood. But people with this deficiency are at a greater risk of forming blood clots.

Causes of Protein C and S Deficiency

It is a congenital disorder.

It causes abnormal clotting of blood.

Symptoms of Protein C and S Deficiency

Symptoms are similar to deep vein thrombosis.

  • Tenderness in the legs or on the site of clotting.
  • Redness of skin.
  • Swelling in the region of the clotting.
  • Warm feeling over the skin.

Laboratory tests:

  • Bleeding time.
  • Clotting time.
  • Partial prothrombine time.
  • Prothrombine time.
  • Test for detecting protein C and S.


  • Early stroke in childhood.
  • Pulmonary embolism.
  • Deep vein thrombosis.

Treatment consists of blood thinning drugs.

Prevention of clotting of blood is very important measure when you have this deficiency. Special care has to be taken when prolonged bed rest is necessary during an illness, after a surgery or a long time stay in the hospital. When you have to sit for a long time in plane or a bus journey you should be careful.