Gastric Lipase | Deficiency And Function Of Gastric Lipase

What Is Gastric Lipase?

Gastric lipase is an enzyme protein which is acidic in nature. It is secreted by the mucosal lining of the fundus of stomach. The pH value of gastric lipase is between 3.0 and 6.0. Gastric lipase is acidic in nature where as pancreatic lipase is alkaline in nature. Due to its acidic content gastric lipase does not require bile to do its function; where as alkaline lipase requires bile for its enzymatic activity.

Function Of Gastric Lipase

  • The food that we eat contains fats; gastric lipase is an enzyme which breaks down the fats found in our food, to make its digestion easy.
  • Lipase is made up of polypeptide and amino acids; its main function is to break the fats cells and make it available to body cells.
  • Gastric lipase acts on the trigyceride molecules to liberate fatty acids molecules. Fatty acid molecules are easily absorbed by the walls of the intestine and transported to blood.

Gastric Lipase

Gastric lipase is very useful when pancreatic lipase i.e. alkaline lipase is unavailable due to pancreatic disease. It does not let down the entire fat digestion process in absence of alkaline lipase.

Though more research is required, it is believed that gastric lipase disinfects the stomach from the swallowed bacteria present in food.

It may due to its acidic nature.

Gastric Lipase Deficiency

In babies gastric lipase helps to break down milk fat molecules, and permeate easy transportation of fat to the tissue cells.

Gastric lipase secretion is made easy by the presence of gastrin in the plasma.

Deficiency of gastric lipase and pancreatic lipase can give rise to many problems such as heart disease, diabetes, deficiency of fat soluble vitamins such as vitamin A, D and E. This is because its deficiency will adversely affect the fat digestion. This is turn will lead to increase in triglyceride and cholesterol in blood.