Acute Myeloid Leukemia: Prognosis, Symptoms And Survival Rate

Acute Myeloid Leukemia is a cancer of the myeloid blood cells, which is characterized by rapid growth and production of abnormal white blood cells. These abnormal cells accumulate in the bone marrow and tend to interfere with the production of normal blood cells. It affects adults and its incidence increases with increasing age. It is a rare disease and is responsible for approximately 1% of all cancer deaths in the United States.

Prognosis Of Acute Myeloid Leukemia

It is a curable condition and the prognosis depends upon several factors. The most important factor is Cytogenetics, or the chromosomal structure of the abnormal cancer cell.

In case the patient has a ‘normal’ cytogenetic structure, the prognosis is good, however, in certain cytogenic abnormalities, the prognosis is poor and there is an increased possibility of relapse.

On an average, as per details from clinical trials, the cure rate is about 30-45%, which depends upon the age of the patient. However, as the age of the patient advances the prognosis are relatively poor.

Acute Myeloid Leukemia Survival Rate

The median age of diagnosis of Acute Myeloid Leukemia is about 63 years and without chemotherapy, the survival rate can be as low as two years.

However, with aggressive chemotherapy, the survival rate increases, again depending upon the age of the patient and their tolerance to aggressive therapy.

Symptoms Of Acute Myeloid Leukemia

The symptoms of Acute Myeloid Leukemia include anemia, increased susceptibility of infections, fatigue, paleness, shortness of breath and excessive bleeding from minor trauma/injury due to low platelet count.