Question: What is life expectancy and prognosis of Scleroderma?
Answer: Scleroderma is a rare autoimmune disease which is characterized by excessive deposition of collagen in skin, blood vessels and the internal organs. It can affect both the genders.
Life Expectancy Of Scleroderma
- In early disease it is difficult to predict the outcome. Once established, scleroderma limited to skin has an excellent prognosis. Complication like pulmonary hypertension and malabsorption may develop late.
- Diffuse scleroderma has poor prognosis with 50% 10 year survival rate.
- Scleroderma is a connective tissue disorder where the skin, tendons and cartilages tighten and become hard. It is a progressive disease. The triggering factor of scleroderma is not known, although some implicate various environmental factors such as, silica dust exposure as in coal miners, exposure to chemicals like vinyl chloride, benzene and toluene.
- Localized thickening of the skin has been reported after administration of certain drugs like pantazocin, bleomycin, which resemble the features of scleroderma.
- Scleroderma involves almost all the organs like, skin, muscles, lungs, gastrointestinal tract, kidneys and heart.
There are two main type of scleroderma, localized and systemic variety.