ALT SGPT Is High: Causes, Treatment for Increased SGPT, SGOT Levels

What are the causes of Elevated or High SGPT & SGOT?

When I did the routine blood test this was the result: SGPT/SGOT level was high. SGPT level is 184, SGOT is 130 and Serum bilirubin is 1.8.

Liver function tests such as SGPT, SGOT, serum alkaline phosphatase, Australia antigen, globulin and albumin are few of the markers of the liver function and its ailments.

These tests are performed for three main reasons:

  • To assist in differentiating whether the jaundice can be treated in a medical conservative way, for example in case of viral hepatitis, or it requires surgical treatment, as in case of obstructive jaundice due to gall bladder stones.
  • For confirming the suspected liver disease.
  • For estimation of the liver damage and as a guide for treating and knowing the prognosis of the liver disease.

Irrespective of the cause, Liver functions are not impaired to the same degree in any one case of liver disease.

SGPT and SGOT are the most important enzymes of the liver parenchymal cells. They are in large numbers in the liver. These enzymes are released in the blood when the liver cells get damaged.

You will have to get further investigation done such as test for hepatitis C, B, and E.  Also get a  sonography of the abdomen done.

Consult a Gastro-enterologist.

Causes of Increased SGPT

The normal range of SGPT is from 20-40 u/l.

Some of the causes of high ALT SGPT are:

  • Liver inflammation (hepatitis A, B, C, Infectious mononeuceosis, acute viral fever, ALCOHOL, pancreatic disorder).
  • Injury to the muscles, as in accidents.
  • Myocardial infarction, congestive heart failure.
  • Acute kidney failure.
  • Certain drugs, like cocaine.
  • Drugs for reducing cholesterol etc.

Causes of Increased SGOT Levels

Causes are almost same as in SGPT rise, but in acute myocardiac infarction, only SGOT gets increased.

For early detection of infective hepatitis, these enzyme are very important markers.

Treatment for High SGPT Levels

Treatment will depend on the cause. If the causative factor is taken care of, then the enzymes will become normal, as in case of viral hepatitis A, B, C. In fact, it guides us to the prognosis of the condition.

Alcohol, certain hepato toxic drugs should be discontinued, if they are the cause.

57 Comments

  1. AS said:

    I was hospitalized after dengue hemorrhage fever, with platelets count down by 10 thousand. After hospitalization for two weeks, I am recuperating and feeling acute weakness. My SGOT and SGPT levels presently are 64 and 68. What are these suggestive of and what care should I take to overcome the weakness also?

    November 11, 2010
    Reply
  2. A N said:

    My SGOT and SGPT levels are 90 and 137 and this due to heavy alcohol consumption. I have now quit drinking. Help me the diet foods to reduce liver enzymes.

    January 7, 2011
    Reply
  3. DK said:

    I am 27, male, unmarried and I have undergone renal transplant one year ago. Now, my SGPT SGOT level has doubled from the normal levels. Suggest me some precautions and diet that would bring my ALT/SGPT SGOT levels to normal.

    February 16, 2011
    Reply
  4. MN said:

    I am 30, male, married. I do not drink alcohol and do not smoke. I just went through a LFT normal test and found that there is an increase in SGOT (60.1) and SGPT (127.3) levels. Also, in Lipid Profile, the test shows VLDL = 28.3, HDL = 56.9, LDL = 83.2 and Triglycerids = 142. What could have caused the Increase in the levels of SGOT and SGPT? Is it a serious problem? What problems can occur due to this and whom should I consult?

    September 3, 2011
    Reply
  5. MG said:

    My sister is 65 and weighs 120 pound. Her blood report shows SGOT 46 and SGPT 47. USG of abdomen shows the liver is enlarged. All other blood tests and ECHO, MRI, ECG are normal. What type of treatment should she take?

    September 4, 2011
    Reply
  6. SM said:

    My SGPT is 130 and SGOT is 65. I am taking medicine as advised by my Gastroenterologist. I have 13 mm fibroid and my menopause has started. Suggest the right diet and recovery process.

    September 8, 2011
    Reply
  7. P said:

    I am suffering from high fever. I got admitted to a hospital. The doctor is saying this is a type of viral fever. Conducted investigations for malaria and typhoid but results are negative. I got blood tests done. My platelets are 1.82. Alkaline phosphate is 226IU/L, SGPT is 195. Fever is now under control but vomiting is consistent and I am not able to digest even water. Is the high ALT SGPT causing this condition?

    October 21, 2011
    Reply
  8. L K said:

    I am 32 and a male. I’ve been exercising for about 12 years. My S.G.P.T and S.G.O.T are 78 and 74 respectively..
    I drink on an average of about twice per month. I was wondering if Whey Protein is the cause of such high level of ALT SGPT. If it is, would lowering quantities be helpful to reduce the values of the SGPT and SGOT?

    November 3, 2011
    Reply
  9. J said:

    I am 33 years old and just got my blood test result. My SGPT level is very high, 763 u/l. Recently, I was detected with gallstone and had pain in the upper right abdominal area. My bilirubin was 36.2 umol/L. What might be the cause of raised of SGPT level? Does the pain in my abdomen occur due to the increase in SGPT level? Or is this all due to the Gallstone?

    November 9, 2011
    Reply
  10. st said:

    I have just got my complete blood examination done. Under the Liver Function Test my SGPT/ALT levels are high and out of range.
    My SGP/ALT level is 51, whereas the range provided by the lab is 0-40.
    Also, under Lipid Profile my Triglycerides level is very high and out of range.
    My reading of Triglycerides is 246, whereas, the range given by lab is 25-150.
    As such, I don’t have any visible symptoms of any problem.
    Help me understand the cause and cure for both the deviations in my blood test.

    November 15, 2011
    Reply
  11. SSI said:

    I am 47, male, married. I am a smoker and I do not drink alcohol. I just went through a LFT normal test and found that there is an increase in SGOT (92.0) levels. Also, in Lipid Profile, the test shows Cholesterol= 334.0 HDL = 37.0 LDL = 257 and Triglycerids = 200. What could have caused the increase in the levels of SGOT and SGPT? Is it a serious problem? What problems can occur due to this and whom should I consult? Also, I am suffering from high blood pressure for the last 15 years and am taking tablets Coversyl 8 mg Loprin 75 mg and Lapigate/Limitrol 10 mg daily.

    January 11, 2012
    Reply
  12. Ran said:

    I am 24 years old and my SGPT is 140. This is the second time my SGPT level has risen so high. I used to be a heavy alcohol drinker earlier, but when I found that my SGPT level was so high the first time, I quit drinking. I take medications to control my SGPT count and it’s level has come down to normal. But 5 months later I found out that the SGPT level has gone up again. What could be the cause of SGPT level elevation? What diet or therapy can you suggest?

    January 20, 2012
    Reply
  13. Jake said:

    I am 24 and SGPT level is very high. I am a smoker and would like to know if smoking can result in high ALT SGPT.

    January 27, 2012
    Reply
  14. EH said:

    The s-ALT (GPT) result is 46 high. I am 43 and do not drink alcohol. I have an extremely uncomfortable stomach. I have cramps also in my stomach. My stool is odorless but light green in color. What do these symptoms indicate?

    February 8, 2012
    Reply
  15. BS said:

    I had to go to urgent care for something else and had my blood tested and found out that my SGOT was 354. I am 44 years old with other health problems also but my doctor tells me not to worry about it. What should I do if my doctor isn’t going to take me seriously? Have I to become very ill before being taken seriously? My numbers have been high for a while, any suggestions on what should I do?

    March 26, 2012
    Reply
  16. KM said:

    I am 47 year old and married. My SGPT level is 60 and SGOt is 49 and I am taking castor (lipitor) 10 mg and tenormine 25 mg. My total cholesterol is 151, Triglycerides is 134, HDL 38 and LDL 86. I am worried about SGPT and SGOT. Kindly advice what can I do for this high level of SGPT and SGOT?

    thanks in advance

    April 1, 2012
    Reply
  17. SL said:

    I am 35yrs old male and I have read that quitting smoking causes flatulence. I quit smoking 23 days ago and have excess gas formation. I checked my blood the SGPT got raised to 76 and creatinine is 1.6.

    April 1, 2012
    Reply
    • PUP said:

      Quitting smoking is good for health. Smoking is not related in any way to flatulence. If you have read or heard somewhere about it, it is completely false. Regarding your SGPT and creatinine level, you should consult your doctor. Do you consume alcohol? If yes, than it may be the reason for raised level. But then too you need to consult your doctor.

      April 7, 2012
      Reply
  18. PD said:

    I am 30 years old male. I occasionally drink alcohol. There is an increase in levels of SGOT 120 and SGPT 160 and my lipid profile is normal. What could be the cause OF the increase in SGOT and SGPT levels? Is it a serious problem? What complications can occur due to this and whom should I consult?

    April 3, 2012
    Reply
  19. KU said:

    My SGPT is 65 and triglyceride is 332. I do not drink or smoke. I eat healthy nutritious diet with less oil. My diet mainly consists of rice and vegetables. I drink two to three cups of coffee in a day. What is the right treatment to bring down both the levels?

    April 3, 2012
    Reply
    • PUP said:

      Your triglyceride level is too high. I suggest you to do the whole lipid profile test, which includes cholesterol level, LDL, HDL, VLDL, etc. Also, do the whole liver profile which includes serum bilirubin, SGPT, serum protein, alkaline phosphatase etc. Omega 3 fatty acids, vitamin C, folic acid and low carbohydrate diet are beneficial in reducing triglyceride. Fish, green tea, fish, turmeric, vegetables and fruits are effective natural foods. But together with it you have to take prescription medication for lowering triglyceride from your doctor.

      April 6, 2012
      Reply
  20. DS said:

    I am 40 years old female and married. I do not drink alcohol and also do not smoke. My ultra Sound report is normal. My test report shows:
    AST/SGOT – 63; ALK/SGPT is 56; Bilirubin Direct – 031.
    Creatinine is 0.4 and A/G RATIO – 1.9.
    Please help me.

    April 9, 2012
    Reply
  21. NP said:

    I am 49 years old male and just got my blood test done and it was found that my SGPT is elevated to 82. I am moderate drinker and only drink over the weekends. I do not have blood pressure issue, Cholesterol problem or any other health related issue. I am in good shape and workout 4 to 5 times a week. Should I worry about this elevated SGPT level?

    April 9, 2012
    Reply
  22. San said:

    My SGOT is 69 and SGPT is 112 an i am taking Tamoxifen for almost 3 years now. Can this be the cause of my elevated SGOT and SGPT? I do not drink any type of alcohol and also do not smoke. Please suggest me some remedy.

    April 10, 2012
    Reply
    • PUP said:

      The commonest side effect of Tamoxifen is hot flashes. Other known side effects include headaches, nausea, vomiting, dryness of vagina, skin rash etc. Regarding raised SGPT and SGOT, you will have to talk to your doctor. There can be some other cause as well for raised SGPT and SGOT.

      April 13, 2012
      Reply
  23. Ger said:

    I am a 30 years old female and married with 2 kids. My SGOT is 128 and SGPT is 195. I was taking Sotret 20m g for the skin problem. Please suggest me how can I control it?

    April 12, 2012
    Reply
  24. JSH said:

    I am 20 years old male and my LFT report shows:
    SGOT is 50; SGPT is 48, S. Alk phosphatase as 108.2
    HBs Ag – non reactive and s. Calcium 8.0
    s. Bilirubin total 0.45; Direct 0.30 and Indirect 0.15.
    I feel lot of fatigue and malaise but my appetite is normal.
    Please advise me what should I do?

    April 14, 2012
    Reply
  25. Jes said:

    My bilirubin direct is 0.16mg/d1 and bilirubin indirect is 0.37mg/d1.
    Alanine transaminase SGPT is 40.60u/1; RDW CV is 15.5 fl and Platelet distribution width is 15.9 %
    Is it a serious problem and can it be controlled by taking medicine? Please guide me on how to bring it to normal.

    April 16, 2012
    Reply
  26. BJ said:

    My SGOT is 124 and SGPT is 142. The pain in my right lower chest started 2 months ago. I consulted my doctor recently and he advised for the above tests. I am not an alcoholic nor do I smoke. My height is 167 cm and weight is 75 Kg and my age is 31. Last few months I used one belt for stomach reduction. Can you suggest me medicines and diet for reducing my abnormal liver function tests.

    May 6, 2012
    Reply
  27. NT said:

    I am 15 years old female. My SGPT is 1510 it is very high. I am getting pain in my liver region along with fever too. What should I do?

    May 8, 2012
    Reply
    • PUP said:

      You should also check your blood for bilirubin, serum alkaline phosphatase, test for hepatitis A and B, blood for malaria parasite. Also an ultrasound of abdomen is necessary. All these tests are suggested to detect if you are suffering from hepatitis or other disease such as malaria. Do these tests as early as you can and follow up with your doctor.

      May 8, 2012
      Reply
  28. SN said:

    I am 13 year old suffering from Hepatitis A. My problem is, my SGPT level is extremely fluctuating, sometimes it increases and sometimes it decreases. What is the matter? What should I do about it?

    May 27, 2012
    Reply
    • PUP said:

      Beside SGPT, you should also consider bilirubin level. If it is hepatitis A, gradually your SGPT level will return back to normal and you should not worry. Rest and light diet is only necessary for recuperation from this disease.

      May 29, 2012
      Reply
  29. HID said:

    I am 32 years of age and I have been suffering from hepatitis B virus for 3 years now. My SGPT is 77, HBV DNA low positive 16650, Hemoglobin is 14.4, anti HBe positive, HBe Ag negative. At present I am having a lot of acidity. I am taking vitamin E, Omeprajol and anti histamine. Please suggest what should I do?

    June 9, 2012
    Reply
  30. DG said:

    I am a 21 year old boy and my SGPT had increased to 44. I think it is due to eating non-veg food and due to eating oily and spicy food. I am getting fever since five days and it ranges from 98 to 102. I have consulted a doctor and he had prescribed me some medicines. Please advise what precautions I should take to get rid of this problem.

    June 27, 2012
    Reply
    • PUP said:

      The first thing which is necessary is to find the underlying cause of fever. Sometime in viral fever there is rise of SGPT level. Continue taking the medicines as prescribed by your doctor. Besides this drink enough water to prevent dehydration. Eat nutritious diet as it will help in fighting the germs which are responsible for fever. Rest for few days is also necessary when you are suffering from fever. Lastly keep regular follow up with your doctor.

      June 28, 2012
      Reply
  31. RS said:

    My SGPT is 3470 IU/L, total bilirubin is 1.9mg/dl and D. Bilirubin is 1.0. How severe is the case? Also what food should I eat and what should I avoid for this?

    July 12, 2012
    Reply
    • PUP said:

      Ideal diet for hepatitis and liver disease is:
      • Green vegetables boiled or steamed.
      • Whole grains.
      • Plenty on fluid intake which may include fresh juice, soups, water, etc.
      • Fresh fruits.
      • Legumes, tofu, tempeh.
      • Chicken, small portion of fish.
      Food that should be avoided in hepatitis:
      • Alcohol in any form.
      • Spicy and oily food.
      • Fast foods.
      • Pain relieving drugs and acetaminophen; you should consult your doctor before taking any medicines as many medicines have liver toxicity.
      • Avoid tea, coffee and other stimulating foods and beverages.
      • Avoid sweets and pastries, cakes and cookies.
      You should check your blood test for hepatitis A, hepatitis B virus.

      July 13, 2012
      Reply
  32. WT said:

    Recently I tested my blood and found SGPT 4680 U/L. Is it very dangerous for my liver?

    July 23, 2012
    Reply
    • PUP said:

      Of course your SGPT level is abnormal. But you should also test other liver tests such as SGOT, Serum Bilirubin, Alkaline phosphatase, etc. All tests put together will help in diagnosing from the problem you are suffering from.

      July 24, 2012
      Reply
  33. SD said:

    I am 23 years old and my SGPT/ ALT rate is 78.0 U/L. I am on medication. Is there any risk?

    August 14, 2012
    Reply
    • PUP said:

      You have not mentioned which medicines you are taking. Talk to your doctor who has prescribed the medicine. He will be able to tell you if these medicines are responsible for the rise of liver enzymes.

      August 15, 2012
      Reply
  34. UKM said:

    My brother has SGOT 124, SGPT 72, alp 133. Is this normal? Can this be cured by medicine? He drinks alcohol daily. Is alcohol responsible for rise in SGOT and SGPT? Should we consult a liver specialist? What should be his diet?

    August 20, 2012
    Reply
    • PUP said:

      Yes, one of the reasons for rise of SGPT and SGOT is alcohol consumption. He should consult a liver specialist. This rise of liver enzymes suggests liver cells are damaged. The first priority is to quit alcohol. You brother should completely stop alcohol. He should eat more of fresh green vegetables, fruits, cereals, less of poultry and meat etc.

      August 20, 2012
      Reply
  35. JJ said:

    Is alcohol the cause for increase in SGOT and SGPT?

    September 21, 2012
    Reply
    • PUP said:

      Alcohol is one of the causes for raised level of SGOT and SGPT. Alcohol damages the liver cells it is considered to be hepatotoxic.

      September 21, 2012
      Reply
  36. JTB said:

    I am 43 years old. My SGPT is 120. I am a known diabetic. Last month I was diagnosed having military tuberculosis. My doctor has prescribed anti-tuberculosis medicine and anti- diabetic medicine. Does anti- TB medicine raise Liver enzymes such as SGOT and SGPT?

    October 23, 2012
    Reply
    • PUP said:

      Yes it is true that few anti tuberculosis medicines are known to raise liver enzymes. However, every individual is not affected who is taking this medicine, those who are affected should regularly follow up with their doctor. If the enzymes are too high and there is untoward symptom such as vomiting and abdominal pain, your physician may think about substituting to some other Anti TB drug.

      October 24, 2012
      Reply
  37. YM said:

    My father is 40 years old male and married. His ultrasound report shows hepatomegaly. His test report shows: AST/SGOT – 45.4u/l; ALK/SGPT is 68.2u/l; Bilirubin direct – 0.9mg/dl.

    October 23, 2012
    Reply
    • PUP said:

      I would like to know the symptoms your father is suffering from. Why was he recommended these liver tests? Indeed, ultrasound does show hepatomegaly, but other blood reports are not absolutely abnormal, though they are slightly on a higher range.

      October 23, 2012
      Reply
  38. Marie said:

    I don’t drink nor smoke. I eat chicken, fish, turkey, and salmon. My cholesterol level is 214 it has never been high.

    November 8, 2012
    Reply
  39. MD said:

    I had jaundice two years ago. After the treatment I was cured of it for a year. Now I am suffering from abdominal discomfort. I consulted my doctor. He checked my SGPT is 65 and Bilirubin is up to 2. He prescribed some medicines. Please provide remedies to lessen SGPT and Bilirubin level.

    February 11, 2017
    Reply
  40. BUS said:

    I am 28 years old. Since few days I am having itching on my body. I went to my doctor and he has given some medicine. My blood report for SGPT is 72. In second report few days afterwards it is 135. I do not drink alcohol or smoke. But I used to eat more spicy food when young. What must be the problem? Is my itching related with raised SGPT level?

    June 8, 2018
    Reply
    • PUP said:

      Since how many days you are getting itching sensation in your body? Your SGPT level is raised than the normal value. You must show this blood test to your doctor. It will help him to understand your problem more clearly. SGPT test is done to know how your liver is functioning. Itching, jaundice, lack of appetite, are some of the symptoms that may occur when your liver is not functioning at its normal pace.

      August 3, 2018
      Reply
  41. JY said:

    My SGPT level is 72, it is slightly higher than the normal value in my blood report. Is it a cause of worry?

    July 4, 2018
    Reply
    • PUP said:

      This isolated lab value of SGPT will not help in interpreting any illness or disorder. You need to have full picture that is complete LFT (liver function test) test which includes blood test for; SGOT, bilirubin, alkaline phosphatase, serum albumin, serum globulin, prothrombin time etc. Many conditions such as viral fever, drinking alcohol, steroid medication, fatty liver, etc can elevate level of SGPT. Hence you must consult a physician or a gastroenterologist for proper diagnosis.

      July 27, 2018
      Reply

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