Lung Transplantation Indications | Selection Criteria for Recipients

Indications of Lung Transplantation

1. Primary vascular disease

• Primary pulmonary hypertension.
• Eisenmenger’s syndrome.

2. End stage pulmonary disease

• Cystic fibrosis.
• Emphysema (especially alpha-1-antitrypsin deficiency).
• Bronchiectasis.
• Pulmonary fibrosis.

Choice of procedure

1. Heart lung transplantation for individuals with suppurative lung disease or pulmonary vascular disease.
2. Single lung transplantation for pulmonary fibrosis.

Selection Criteria for Lung Transplant Recipients

1. Progressive end stage disease which is unresponsive to medical therapy.
2. Estimated life expectancy is less than 12 to 18 months.
3. Age should be less than 45 years for heart transplantation and less than 60 years for single lung transplantation.
4. No significant impairment of renal or hepatic function.
5. No significant coronary artery disease (for lung transplantation only).
6. Ability to comply with medication.
7. No evidence of other progressive systemic disease.
8. Patients requiring assisted ventilation are generally not suitable.

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