Types of Lung Cancer | Classification of Lung Cancer

Types and classifications of lung cancer

Many classifications of lung cancer have been proposed. Lung cancer survival rate varies from person to person and depends on the type of cancer.
The classification or types of lung cancer as recommended by world health organization (WHO) are

Epidermoid – squamous cell carcinoma

  • Spindle cell variant

Small cell anaplastic (oat cell) carcinoma

  • Oat cell carcinoma
  • Intermediate type
  • Combined oat cell carcinoma

Adenocarcimona

  • Acinar -  with or without mucin formation
  • Papillary
  • Bronchoalveolar

Large cell carcinoma

  • Giant cell carcinoma
  • Clear cell carcinoma

Combined epidermoid and adenocarcinoma

  • These constitute over 95% of all lung cancer tumors.
  • Others include carcinoid, bronchial gland tumors like cylindromas and adenoid cystic carcinoma.

However, epidermoid carcinoma is still the most common type of lung cancer.

Epidermoid or squamous cell carcinoma

  • Epidermoid carcinoma has a relatively slow rate of growth and often presents with local symptoms.

Small cell carcinoma

  • It has a high rate of growth and proves rapidly fatal due to early metastasis to the regional mediastinal lymph nodes and to distant organs.
  • At the time of diagnosis itself, in over two out of  the three persons, there is an evidence of distant metastatsis  to the liver, central nervous system and bone.
  • They are more often central than peripheral.

Oat cell carcinoma

  • Oat cell (classical) type is characterized by round or oval nuclei with a scanty cytoplasm.

Intermediate type

  • The intermediate type shows cells that are less regular in shape.

Adenocarcinomas

  • Adenocarcinomas are the most commonly present as mild zone or peripheral mass lesions.
  • Poorly differentiated adenocarcinomas tend to metastasize early and have a poor prognosis.

Large cell carcinoma

  • Large cell carcinomas lack any characteristics to label them as squamous cell carcinoma or adeno-carcinoma.
  • They are made up of large malignant cells with abundant cytoplasm.

2 comments


  1. R S

    Please provide some details of
    1.what is “adenocarcinoma lung massive pleural effusion” as related to lung cancer,
    2. what causes it
    3. treatments available
    4. contact details of the best hospital and doctors in the world for treating this ailment?

    • Salina

      Adenocarcinoma is a common malignant tumor of the lung. It is manifested as the following:
      o cough
      o chest pain
      o coughing blood
      o chest infection
      o weight loss
      o hoarseness
      o shortness of breath

      Causes:
      1. active smoking
      2. passive smoking
      3. certain occupational hazards – working with asbestos, arsenic, chromium, iron oxide, coal tar, and radiation.
      Pleural effusion occurs in cases of carcinoma, when excessive fluid gets accumulated in the pleural space.

      Treatment:
      1. surgical intervention becomes necessary.
      2. high dose radiotherapy is also given
      3. single or combination chemotherapy.
      4. laser therapy

      Care:
      o Candidiasis of the mouth is common. It should be looked for, and treated.
      o The diet is of absolute essence. Plenty of fresh fruits and vegetables are recommended. Foods which are packed with anti-oxidants (broccoli, strawberries, and tomatoes) should be consumed liberally. Turmeric is known for its anti-cancer properties. Increase its intake.
      o Counseling the patient and the family is required.

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