Question: What is meant by theophylline metabolism? Which are the factors that can slow down theophylline metabolism? Can one use a different brand of theophylline from the one the doctor prescribed?
Metabolism Of Theophylline
The rate at which the body breaks down theophylline is called theophylline metabolism. If an individual’s body metabolizes theophylline slowly then he will need less theophylline as compared to someone who metabolizes it quickly. Children usually metabolize theophylline faster than adults, so they need more medication per pound of body weight. The body of a person who smokes or is exposed to cigarette smoke, burns theophylline more quickly.
The other factors that can slow theophylline metabolism include heart disease; fevers and viral infections; liver disease and certain drugs like oral contraceptives, ulcer drugs, antibiotics like erythromycin and a number of heart medications. Under the above circumstances a person requires less theophylline. An individual has to check with his doctor if any of the above situations applies to him. If situation demands the doctor may suggest a reduction in theophylline dose and may even suggest a blood test.
Different brands of theophylline differ slightly in their appearance and concentration. So most doctors believe it is better to stick to the same brand that is prescribed to an individual after a thorough analysis.
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