Symptoms of Chronic Pancreatitis | Tropical Pancreatitis | Pancreatic Cancer

Symptoms of Chronic Pancreatitis

  • Alcoholic chronic pancreatitis usually presents in 4th or 5th decades of life with a male preponderance.
  • Tropical pancreatitis usually affects in younger age group.

Abdominal pain

  • It is the main symptom in majority of patients.
  • Classical pain is epigastria, persistent, precipitated by heavy meals, with radiation to the back and is relieved by sitting up and leaning forwards.
  • Pain may be intermittent and atypical in location.
  • Vomiting may occur. In about 20% of cases, the disease is painless.

Diabetes mellitus

  • Overt diabetes mellitus occurs in about 1/3rd of patients but over 50% will have glucose intolerance.
  • Diabetes is more frequent in tropical pancreatitis.
  • Many patients require insulin for diabetes control.
  • Incidence of ketoacidosis is less.

Anorexia

  • Anorexia and weight loss are common.
  • Steatorrhea accounts for weight loss in chronic pancreatitis.
  • In tropical pancreatitis, weight loss is not seen due to low fat intake.
  • Severe weight loss associated with persistent pain should raise the possibility of super-added pancreatic cancer.

Jaundice

  • Obstructive jaundice is more common when complications like pseudo cyst or tumor sets in.
  • In alcoholic pancreatitis, pseudo cyst occurs in 20-40% of cases, while in tropical pancreatitis the incidence is only 5-7%.

Physical signs

  • There are very few physical signs.
  • Epigastric tenderness may be present.
  • Jaundice may be present when biliary obstruction sets in.
  • Emaciation and signs of nutritional or vitamin deficiency are present in extreme cases.
  • A palpable mass indicated pseudo cyst or rarely malignancy.

 

 

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